Personal information

T cells, immunometabolism, immunology, diabetes
Netherlands

Activities

Employment (6)

University of Rijeka, School of Medicine: Rijeka, HR

2013-06-01 to present | Associate Professor (Histology & Embryology)
Employment
Source: Self-asserted source
Felix M Wensveen

Universiteit van Amsterdam: Amsterdam, Noord-Holland, NL

2014-02-01 to 2017-01-31 | Veni Laureate (Experimental Immunology)
Employment
Source: Self-asserted source
Felix M Wensveen

Sveuciliste u Rijeci Medicinski fakultet: Rijeka, HR

2011-06-01 to 2013-05-31 | Marie Curie (IEF) Fellow (Histology & Embryology)
Employment
Source: Self-asserted source
Felix M Wensveen

Sveuciliste u Rijeci Medicinski fakultet: Rijeka, HR

2010-09-01 to 2011-05-31 | Postdoc (Histology & Embryology)
Employment
Source: Self-asserted source
Felix M Wensveen

Universiteit van Amsterdam: Amsterdam, Noord-Holland, NL

2006-03-01 to 2010-07-01 | PhD. student (Experimental Immunology)
Employment
Source: Self-asserted source
Felix M Wensveen

Vrije Universiteit Amsterdam: Amsterdam, Noord-Holland, NL

2004-09-01 to 2004-11-01 | Research Technician (Virology & Gene Therapy)
Employment
Source: Self-asserted source
Felix M Wensveen

Education and qualifications (3)

Universiteit van Amsterdam: Amsterdam, Noord-Holland, NL

2006-03-01 to 2010-11-05 | PhD. (Experimental Immunology)
Education
Source: Self-asserted source
Felix M Wensveen

Universiteit van Amsterdam: Amsterdam, Noord-Holland, NL

2003-09-01 to 2006-02-28 | MSc. of Biomedical Science
Education
Source: Self-asserted source
Felix M Wensveen

Universiteit van Amsterdam: Amsterdam, Noord-Holland, NL

2000-09-01 to 2003-08-31 | BSc. of Biomedical Science
Education
Source: Self-asserted source
Felix M Wensveen

Funding (4)

Rewriting memory; Manipulation of T cell memory to enhance vaccine efficiency

2017-07 to 2021-06 | Grant
National Science Foundation (Opatija, VA, HR)
GRANT_NUMBER:

IP-06-2016-8027

Source: Self-asserted source
Felix M Wensveen

Memory control; Molecular mechanisms that control the scope of immunological memory

2015-02 to 2017-02 | Grant
European Commission (Brussels, Europe, BE)
GRANT_NUMBER:

630827

Source: Self-asserted source
Felix M Wensveen

Memory control; Molecular mechanisms that control the scope of immunological memory

2014-02 to 2017-02 | Grant
NWO (Den Haag, Netherlands, NL)
GRANT_NUMBER: 91614029
Source: Self-asserted source
Felix M Wensveen

Memory Control; The role of NKG2D and the T-cell receptor in memory T cell biology

2011-06 to 2013-06 | Grant
European Commission (Brussels, Europe, BE)
GRANT_NUMBER:

274995

Source: Self-asserted source
Felix M Wensveen

Works (46)

The “Domino effect” in MASLD: The inflammatory cascade of steatohepatitis

European Journal of Immunology
2024-04 | Journal article
Contributors: Karlo Mladenić; Maja Lenartić; Sonja Marinović; Bojan Polić; Felix M. Wensveen
Source: check_circle
Crossref

Inflammageing mediated by cytotoxic lymphocytes is associated with diabetes duration

Diabetes Research and Clinical Practice
2024-01 | Journal article
Contributors: Dora Gašparini; Felix M. Wensveen; Tamara Turk Wensveen
Source: check_circle
Crossref

Vaccination provides superior in vivo recall capacity of SARS-CoV-2-specific memory CD8 T cells

Cell Reports
2023-04 | Journal article
Contributors: Inga Kavazović; Christoforos Dimitropoulos; Dora Gašparini; Mari Rončević Filipović; Igor Barković; Jan Koster; Niels A. Lemmermann; Marina Babić; Đurđica Cekinović Grbeša; Felix M. Wensveen
Source: check_circle
Crossref

Chronic lymphocytic leukemia presence impairs antigen-specific CD8+ T-cell responses through epigenetic reprogramming towards short-lived effectors

Leukemia
2023-03 | Journal article
Contributors: Anne W. J. Martens; Inga Kavazović; Mia Krapić; Su Min Pack; Ramon Arens; Aldo Jongejan; Perry D. Moerland; Eric Eldering; Gerritje J. W. van der Windt; Felix M. Wensveen et al.
Source: check_circle
Crossref

Activation of Granulocytes in Response to a High Protein Diet Leads to the Formation of Necrotic Lesions in the Liver

Metabolites
2023-01-19 | Journal article
Contributors: Ante Benić; Sanja Mikašinović; Felix M. Wensveen; Bojan Polić
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Extreme anaerobic exercise causes reduced cytotoxicity and increased cytokine production by peripheral blood lymphocytes

Immunology Letters
2022-08 | Journal article
Contributors: Dora Gašparini; Inga Kavazović; Igor Barković; Vitomir Maričić; Viktor Ivaniš; Dijana Travica Samsa; Viktor Peršić; Bojan Polić; Tamara Turk Wensveen; Felix M. Wensveen
Source: check_circle
Crossref

Hyperglycemia and Not Hyperinsulinemia Mediates Diabetes-Induced Memory CD8 T-Cell Dysfunction

Diabetes
2022-04-01 | Journal article
Contributors: Inga Kavazović; Mia Krapić; Ammarina Beumer-Chuwonpad; Bojan Polić; Tamara Turk Wensveen; Niels A. Lemmermann; Klaas P.J.M. van Gisbergen; Felix M. Wensveen
Source: check_circle
Crossref

Immunological Mechanisms of Sickness Behavior in Viral Infection

Viruses
2021-11-08 | Journal article
Contributors: Mia Krapić; Inga Kavazović; Felix M. Wensveen
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Hobit identifies tissue-resident memory T cell precursors that are regulated by Eomes

Science Immunology
2021-08-10 | Journal article
Contributors: Loreto Parga-Vidal; Felix M. Behr; Natasja A. M. Kragten; Benjamin Nota; Thomas H. Wesselink; Inga Kavazović; Laura E. Covill; Margo B. P. Schuller; Yenan T. Bryceson; Felix M. Wensveen et al.
Source: check_circle
Crossref

Severe Lipoatrophy in a Patient With Type 2 Diabetes in Response to Human Insulin Analogs Glargine and Degludec: Possible Involvement of CD4 T Cell–Mediated Tissue Remodeling

Diabetes Care
2020-02-01 | Journal article
Contributors: Tamara Turk Wensveen; Dora Fučkar Čupić; Dubravka Jurišić Eržen; Bojan Polić; Felix M. Wensveen
Source: check_circle
Crossref

'Beauty and the beast' in infection: How immune-endocrine interactions regulate systemic metabolism in the context of infection.

European journal of immunology
2019-05-27 | Journal article
Source: Self-asserted source
Felix M Wensveen

Croatian Immunological Society: Our half century.

European journal of immunology
2019-02-01 | Journal article
Source: Self-asserted source
Felix M Wensveen

Cheating the Hunger Games; Mechanisms Controlling Clonal Diversity of CD8 Effector and Memory Populations.

Frontiers in immunology
2018-11-29 | Journal article
Source: Self-asserted source
Felix M Wensveen

NK cell receptor NKG2D sets activation threshold for the NCR1 receptor early in NK cell development.

Nature immunology
2018-09 | Journal article
Contributors: Jelenčić V; Šestan M; Kavazović I; Lenartić M; Marinović S; Holmes TD; Prchal-Murphy M; Lisnić B; Sexl V; Bryceson YT et al.
Source: Self-asserted source
Felix M Wensveen via Europe PubMed Central

Virus-Induced Interferon-γ Causes Insulin Resistance in Skeletal Muscle and Derails Glycemic Control in Obesity.

Immunity
2018-06 | Journal article
Contributors: Šestan M; Marinović S; Kavazović I; Cekinović Đ; Wueest S; Turk Wensveen T; Brizić I; Jonjić S; Konrad D; Wensveen FM et al.
Source: Self-asserted source
Felix M Wensveen via Europe PubMed Central

NKG2D: A Master Regulator of Immune Cell Responsiveness.

Frontiers in immunology
2018-03 | Journal article
Contributors: Wensveen FM; Jelenčić V; Polić B
Source: Self-asserted source
Felix M Wensveen via Europe PubMed Central

NKG2D stimulation of CD8+ T cells during priming promotes their capacity to produce cytokines in response to viral infection in mice

European Journal of Immunology
2017-07 | Journal article
Contributors: Inga Kavazović; Maja Lenartić; Vedrana Jelenčić; Slaven Jurković; Niels A.W. Lemmermann; Stipan Jonjić; Bojan Polić; Felix M. Wensveen
Source: check_circle
Crossref

NKG2D: A versatile player in the immune system.

2017-04 | Journal article
Contributors: Jelenčić V; Lenartić M; Wensveen FM; Polić B
Source: Self-asserted source
Felix M Wensveen via Europe PubMed Central

NKG2D Promotes B1a Cell Development and Protection against Bacterial Infection

The Journal of Immunology
2017-02-15 | Journal article
Contributors: Maja Lenartić; Vedrana Jelenčić; Biljana Zafirova; Mateja Ožanič; Valentina Marečić; Slaven Jurković; Veronika Sexl; Marina Šantić; Felix M. Wensveen; Bojan Polić
Source: check_circle
Crossref

Erratum: Antigen-affinity controls pre-germinal center B cell selection by promoting Mcl-1 induction through BAFF receptor signaling.

Scientific reports
2017-01 | Journal article
Contributors: Wensveen FM; Slinger E; van Attekum MH; Brink R; Eldering E
Source: Self-asserted source
Felix M Wensveen via Europe PubMed Central

Nonalcoholic fatty liver disease - A multisystem disease?

2016-11 | Journal article
Contributors: Mikolasevic I; Milic S; Turk Wensveen T; Grgic I; Jakopcic I; Stimac D; Wensveen F; Orlic L
Source: Self-asserted source
Felix M Wensveen via Europe PubMed Central

Antigen-affinity controls pre-germinal center B cell selection by promoting Mcl-1 induction through BAFF receptor signaling.

Scientific reports
2016-10 | Journal article
Contributors: Wensveen FM; Slinger E; van Attekum MH; Brink R; Eldering E
Source: Self-asserted source
Felix M Wensveen via Europe PubMed Central

Chronic lymphocytic leukemia development is accelerated in mice with deficiency of the pro-apoptotic regulator NOXA.

2016-09 | Journal article
Contributors: Slinger E; Wensveen FM; Guikema JE; Kater AP; Eldering E
Source: Self-asserted source
Felix M Wensveen via Europe PubMed Central

NKG2D ligands mediate immunosurveillance of senescent cells.

2016-02 | Journal article
Contributors: Sagiv A; Burton DG; Moshayev Z; Vadai E; Wensveen F; Ben-Dor S; Golani O; Polic B; Krizhanovsky V
Source: Self-asserted source
Felix M Wensveen via Europe PubMed Central

Interactions between adipose tissue and the immune system in health and malnutrition.

2015-09 | Journal article
Contributors: Wensveen FM; Valentić S; Šestan M; Wensveen TT; Polić B
Source: Self-asserted source
Felix M Wensveen via Europe PubMed Central

The "Big Bang" in obese fat: Events initiating obesity-induced adipose tissue inflammation.

European Journal of Immunology
2015-09 | Journal article
Source: Self-asserted source
Felix M Wensveen
grade
Preferred source (of 2)‎

NK cells link obesity-induced adipose stress to inflammation and insulin resistance.

Nature Immunology
2015-04 | Journal article
Source: Self-asserted source
Felix M Wensveen
grade
Preferred source (of 2)‎

BH3-only protein Noxa contributes to apoptotic control of stress-erythropoiesis.

Apoptosis
2013-11 | Journal article
Source: Self-asserted source
Felix M Wensveen
grade
Preferred source (of 2)‎

Superior induction and maintenance of protective CD8 T cells in mice infected with mouse cytomegalovirus vector expressing RAE-1γ.

Proceedings of the National Academy of Sciences of the USA
2013-10 | Journal article
Source: Self-asserted source
Felix M Wensveen
grade
Preferred source (of 2)‎

NKG2D induces Mcl-1 expression and mediates survival of CD8 memory T cell precursors via phosphatidylinositol 3-kinase.

Journal of Immunology
2013-08 | Journal article
Source: Self-asserted source
Felix M Wensveen
grade
Preferred source (of 2)‎

CD27-CD70 costimulation controls T cell immunity during acute and persistent cytomegalovirus infection.

Journal of Virology
2013-06 | Journal article
Source: Self-asserted source
Felix M Wensveen
grade
Preferred source (of 2)‎

Pro-apoptotic protein Noxa regulates memory T cell population size and protects against lethal immunopathology.

Journal of Immunology
2013-02 | Journal article
Source: Self-asserted source
Felix M Wensveen
grade
Preferred source (of 2)‎

Mouse Hobit is a homolog of the transcriptional repressor Blimp-1 that regulates NKT cell effector differentiation.

Nature Immunology
2012-09 | Journal article
Source: Self-asserted source
Felix M Wensveen
grade
Preferred source (of 2)‎

The fourth dimension in immunological space: how the struggle for nutrients selects high-affinity lymphocytes.

Immunological Reviews
2012-09 | Journal article
Source: Self-asserted source
Felix M Wensveen
grade
Preferred source (of 2)‎

CD70-driven costimulation induces survival or Fas-mediated apoptosis of T cells depending on antigenic load.

Journal of Immunology
2012-05 | Journal article
Source: Self-asserted source
Felix M Wensveen
grade
Preferred source (of 2)‎

BH3-only protein Noxa regulates apoptosis in activated B cells and controls high-affinity antibody formation.

Blood
2012-02 | Journal article
Source: Self-asserted source
Felix M Wensveen
grade
Preferred source (of 2)‎

Regulation of immune cell function and differentiation by the NKG2D receptor.

Cellular and Molecular Life Sciences
2011-11 | Journal article
Source: Self-asserted source
Felix M Wensveen
grade
Preferred source (of 2)‎

Chronic IFN-γ production in mice induces anemia by reducing erythrocyte life span and inhibiting erythropoiesis through an IRF-1/PU.1 axis.

Blood
2011-09 | Journal article
Source: Self-asserted source
Felix M Wensveen
grade
Preferred source (of 2)‎

Apoptosis induced by overall metabolic stress converges on the Bcl-2 family proteins Noxa and Mcl-1.

Apoptosis
2011-07 | Journal article
Source: Self-asserted source
Felix M Wensveen
grade
Preferred source (of 2)‎

The costimulatory molecule CD27 maintains clonally diverse CD8(+) T cell responses of low antigen affinity to protect against viral variants.

Immunity
2011-07 | Journal article
Source: Self-asserted source
Felix M Wensveen
grade
Preferred source (of 2)‎

WNT signaling controls expression of pro-apoptotic BOK and BAX in intestinal cancer.

Biochemical and Biophysical Research Communications
2011-03 | Journal article
Source: Self-asserted source
Felix M Wensveen
grade
Preferred source (of 2)‎

Apoptosis threshold set by Noxa and Mcl-1 after T cell activation regulates competitive selection of high-affinity clones.

Immunity
2010-06 | Journal article
Source: Self-asserted source
Felix M Wensveen
grade
Preferred source (of 2)‎

Human CD34-derived myeloid dendritic cell development requires intact phosphatidylinositol 3-kinase-protein kinase B-mammalian target of rapamycin signaling.

Journal of Immunology
2010-06 | Journal article
Source: Self-asserted source
Felix M Wensveen
grade
Preferred source (of 2)‎

GITR triggering induces expansion of both effector and regulatory CD4+ T cells in vivo.

Journal of Immunology
2009-06 | Journal article
Source: Self-asserted source
Felix M Wensveen
grade
Preferred source (of 2)‎

Crosstalk among Bcl-2 family members in B-CLL: seliciclib acts via the Mcl-1/Noxa axis and gradual exhaustion of Bcl-2 protection.

Cell Death and Differentiation
2007-11 | Journal article
Source: Self-asserted source
Felix M Wensveen
grade
Preferred source (of 2)‎

Genetic targeting of adenovirus vectors using a reovirus sigma1-based attachment protein.

Molecular Therapy
2006-05 | Journal article
Source: Self-asserted source
Felix M Wensveen
grade
Preferred source (of 2)‎

Peer review (3 reviews for 2 publications/grants)

Review activity for eLife (1)
Review activity for Nature metabolism. (2)